Drug safety update: Topical miconazole, including oral gel: reminder of potential for serious interactions with warfarin
The Medicines and Healthcare Products Regulatory Agency (MHRA) has issued a drug safety update reminding healthcare professionals of the potential for serious interactions between topical miconazole, including oral gel and warfarin.
The MHRA are currently reviewing available data for this interaction to determine whether further measures are required to minimise the risks to patients. This review follows a coroner’s report of a death, which may have been partly due to the coadministration of miconazole oral gel and warfarin.
of the update are available on the MHRA website.