mixture-of-tablets

TABLETTING TECHNOLOGY COURSE

20 - 22 November 2017, London

Tabletting technology for the pharmaceutical industry is a 3-day event offering delegates the unique opportunity to discuss real challenges faced in day-to-day work with industry experts.

The course is a well established and intensive course, designed to provide attendees with an in depth study of the formulation, production and drug-release characteristics of pharmaceutical tablets.

It's an introduction to tabletting and the associated processes and delegates will leave the course with knowledge that they will be able to apply to day-to-day problems in tabletting.

Fees

 

Early bird discount

Price after 29 September

Member

£1,200 £1,300

Non-member

£1,500 £1,600

Book today to save £100!

Book now


Save £300 on the cost of your ticket by becoming a member of the RPS.

Programme

09:30 Registration
10:15

Introduction
Kendal Pitt, GlaxoSmithKline

10:45

Granules and tablets: A review of the reasons for granulation and tabletting, the classes of excipients and principles of operation of tabletting machines
Graham Buckton, University of London

11:30

Material properties of importance for tabletting (I)
Graham Buckton, University of London 

12:15

Material properties of importance for tabletting (II)
Graham Buckton, University of London 

12:45 Lunch
13:45

A brief introduction to modified release
Graham Buckton, University of London 

14:15

Dissolution testing
Graham Buckton, University of London

14:45

Key aspects of tablet formulation and characterisation
Michael Wilkins, Almac Pharma Services

15:45 Tea & coffee
16:00

Problem based learning 1: Active Pharmaceutical Ingredient (API)
Kendal Pitt, GlaxoSmithKline

Problem based learning 2: Formulation development
Michael Wilkins, Almac Pharma Services

16:45 Problem based learning (TBC)
17:30 (TBC)
18:00 Close
18:15 - 21:30 Social programme

 

Book now

08:30

Tabletting machines and in-process control
Brian Helsdon, Consultant 

09:30

Punch design
Steve Osborn, Director, I Holland

10:30 Tea and coffee
10:45

Compaction simulation
Kendal Pitt, GlaxoSmithKline

11:45

Packaging: Key concepts
Michael Wilkins, Almac Pharma Services

12:30 Lunch
13:30

Roller compaction
Kendal Pitt, GlaxoSmithKline

14:30

Production workshop
Sander van den Ban, GlaxoSmithKline 
Tesh Patel, Astellas

15:30 Tea and coffee
15:45

Production workshop
Sander van den Ban, GlaxoSmithKline 
Tesh Patel, Astellas

16:45 Close

 

Book now

08:30

Process Analytical Technolgy (PAT) applied to tabletting
Sander van den Ban, GlaxoSmithKline

09:30

Granulation equipment and end point control automation
Christian Seiler, PharmaXP Consulting

10:15 Tea and coffee
10:30

Scale-up of tablet manufacturing processes and transfer from R&D to production
Christian Seiler, PharmaXP Consulting

11:15

An introduction to pharmaceutical coating technology
Marshall Whiteman, Quindell Consulting

12:15 Lunch
13:15

Coating-advances in techniques of formulation
Marshall Whiteman, Quindell Consulting

14:00

Compaction characterisation and process understanding
Kendal Pitt, GlaxoSmithKline

15:00 Concluding discussion
15:15 Close

 

Book now

Speakers

Graham Buckton

Emeritus Professor of Pharmaceutics, UCL School of Pharmacy

Graham obtained his PhD from King’s College London in 1985 and was awarded the degree of Doctor of Science by the University of London in 1997, for “Materials characterisation of importance to drug delivery”.   In 2013 he became a Chartered Director of the Institute of Directors.

As an Emeritus Professor of the UCL School of Pharmacy, Graham retains a research group at the school.  The research relates to the amorphous state, powder processing, surface science, solid oral dosage forms, inhalation drug delivery and modified release dosage forms. He has published a book and over 175 papers on these themes. He has received the Pfizer Award, the British Pharmaceutical Conference Science Medal and the Stig Sunner Award (for “outstanding work in Thermochemistry and Thermal Analysis” from the US Calorimetry Conference).  

Professor Buckton is a fellow of the Royal Pharmaceutical Society, Royal Society of Chemistry, AAPS and APSGB. He is also a Freeman of the City of London.

Brian Helsdon

Consultant / Product Expert

An engineer with 45+ years’ experience of the Manesty / Bosch  products, Brian Helsdon has a wide knowledge of tableting equipment gained as result of many years working within the production and engineering departments at Manesty in a number of senior roles. 

Brian was responsible for Manesty's customer training and product support worldwide up to his retirement in November 2012.

He now as part of Bosch Management Support (BMS) offers consulting, support & training in tablet compression technology, tablet coating equipment and tablet tooling. 

Tesh Patel

Executive Director, Head of QA – Europe, Middle East & Africa, Astellas Pharma EMEA

Dr Patel is a PhD Pharmacist from Portsmouth and Manchester Universities, an EU Qualified Person and currently Executive Director, Head of Quality Assurance - EMEA; Astellas Pharma EMEA.

Prior to Astellas, he worked for Abbott Laboratories for fourteen years and ICI / Zeneca Pharmaceuticals for nine years. At Abbott, he held positions of Technical Services Manager, Manufacturing Manager, QA Product Surveillance Manager, Divisional Quality Manager (Europe/Japan) and Commercial QA Manager (Europe). 

Dr Patel's specialist field is in the development and manufacture of solid and liquid dosage pharmaceuticals, and is a member of both the Royal Societies of Chemistry and Pharmacy and of the Chartered Management Institute.

Kendal Pitt

Senior technical director in Global manufacturing, GlaxoSmithKline 

Kendal G. Pitt, Ph.D (London University), B.Pharm (University of Nottingham), is a Senior Technical Director in Global Manufacturing and Supply for GlaxoSmithKline based at Ware, UK. 


He is a a Fellow of the Royal Pharmaceutical Society (FRPharmS) and a Fellow of the Academy of Pharmaceutical Sciences (FAPS). Kendal has worked in the Pharmaceutical Industry for over 30 years, with Wellcome Foundation Ltd., Roche Pharmaceuticals and more recently for Merck. He has headed groups in both the United States and Great Britain and has led project teams responsible for the successful filing and launch of both tablets and freeze-dried oral dosage forms.

Primary research interests are in powder compaction, powder flow and granulation process optimisation, including the use of compaction simulators in tablet and capsule product development. He has additionally published in the areas of formulation and design for nasal delivery of pharmaceuticals and on statistical design of experiments, and has co-authored chapters on formulation, tabletting and on strength testing. 

Christian Seiler

Chairman, Pharma Xp Consulting Limited and Global Technical Head, Cmc / Pharmaceutical Development, Viiv Healthcare

Christian holds a masters degree in Chemical Engineering from the University of Karlsruhe, Germany, and a PhD in Chemical Engineering from the University of Birmingham, UK. 

Christian has been working in the pharmaceutical industry for the past 17 years and is currently Global Technical Head, CMC / Pharmaceutical Development, of ViiV Healthcare, a pharmaceutical company with 100% focus on HIV therapies, which is owned by GlaxoSmithKline, Pfizer & Shionogi. He is also chairman of Pharma XP Consulting Limited, a company providing technical & strategic consultancy to the pharmaceutical sector, for which he served as Managing Director from 2014 to 2016 (until joining the staff of ViiV Healthcare). Prior to this, Christian worked in the Research Laboratories of Merck/MSD (2000-2014), where he was a Senior Principal Scientist, Formulation Sciences group leader, Controlled Release Centre of Excellence leader (2007-2013) and member of the Innovation Strategy Board in Pharmaceutical Sciences & Clinical Supply (2011-2014).

Christian has been active in the scientific community for many years, having presented at many conferences, supervised a number of University research projects (including PhDs) and served on various scientific committees, mainly for the Institution of Chemical Engineers (IChemE), the Royal Society of Chemistry (RSC) and the Controlled Release Society (CRS).

Christian’s primary research interests / expertise are in the areas of powder granulation, particle coating and oral controlled release formulation development, with broad experience in all aspects of oral solid dosage form development.

Sander van den Ban

Technical Director & Product Lead in Global Manufacturing & Supply, GlaxoSmithKline

Sander holds a masters degree in “Chemical Technology and Materials Science” from the University of Delft, the Netherlands and graduated with distinction in the field of explosion science. 

He has worked in the Pharmaceutical Industry for over 10 years in various positions as Chemical Process Engineer in Research and Development, Engineering Technology and Capital Management, and Process Design and Development. He has been a Product Lead in the Oral Solid Dose Centre of Excellence since 2009 and accountable for the transfer and introduction of well understood reliable manufacturing processes for tablet dosage forms from R&D into manufacturing with particular focus on QbD and interaction with US, European and International regulatory agencies.

Venue

VIL_7781_wb_outsidetree

Royal Pharmaceutical Society
66 East Smithfield
London
E1W 1AW

Get directions

Sponsors

Honeywell-red