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Is anyone having problems with trials using iv bortezomib?
This site is looking to move to sc administration and consider it ethically inappropriate (apparently the side effect profile of sc admin is much better than iv). It is also considered too greater risk to have both sc and iv admin being used at the same site for different patients.
We have approached the trial study sponsors who are not amenable to the use of sc bortezomib and are not planning to change their protocol in the near future.
A risk assessment is in process but it would be useful to know what other sites are doing. Any feedback would be helpful.
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