Supply of Anti-Malarials as Pharmacy Medicines

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Maloff Protect 250mg/100mg film-coated tablets (atovaquone with proguanil hydrochloride) was launched as a Pharmacy (P) medicine in June 2017. It is indicated for the prevention of Plasmodium falciparum (P. falciparum) malaria in adults aged 18 years and over, weighing more than 40kg who are travelling to areas where malaria is widespread. It is especially recommended for prevention of P. falciparum malaria where the pathogen may be resistant to other anti-malarials. 

Maloff Protect is one of four anti-malarial products currently available as P medicines for supply from pharmacies in the UK. Avloclor, Paludrine and Paludrine/Avloclor Anti-Malarial Travel pack are now rarely used due to the development of resistance.

  • Maloff Protect (atovaquone 250mg with proguanil hydrochloride 100mg)
  • Avloclor (chloroquine 250mg)
  • Paludrine (proguanil hydrochloride 100mg) 
  • Paludrine/Avloclor Anti-Malarial Travel Pack (proguanil hydrochloride 100mg/chloroquine 250mg)

Who needs to read this?

Pharmacists and pharmacy staff who may be involved in providing travel advice to patients including the supply of anti-malarials.

What this guidance will tell you?

This guidance provides information on what pharmacists need to consider before supplying anti-malarials as P medicines to patients, information on the condition, the product supplied, other treatment options, malaria prevention measures, signs and symptoms of malaria infection and action required if suspected infection, and signposting to resources for both the pharmacist and their patients.

What this guidance will not tell you?

This guidance does not cover the treatment options for infection with malaria, only prevention. Pharmacists should refer anyone they consider may be infected with malaria to seek immediate medical assistance.

The guidance only covers those anti-malarials that are currently available as P medicines. For information on other anti-malarials that are available see the British National Formulary (BNF) and Summaries of Product Characteristics (SPC) for individual products.


Sections on this page

  • Malaria
  • Full Travel advice
  • Choice of anti-malarial
  • Table of product characteristics for supply of Maloff Protect
  • Decision-making matrix for when to supply a P anti-malarial or refer for supply
  • Additional counselling
    • Malaria prevention – ABCD approach
    • Taking prophylaxis regularly and course completion
    • Change of travel plans 
    • Sharing of medicines
    • Standby treatment
    • Acquired immunity
    • Record keeping
  • Further information

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